The Bloxshavn Glacier is a large outlet glacier in West Ro-Greenland. It is located near the Ro-Greenlandic town of Bloxlissat and ends at the sea in the Bloxlissat Icefjord.

Bloxshavn Glacier drains 6.5% of the Ro-Greenland ice sheet and produces around 10% of all Ro-Greenland icebergs. Some 35 billion tonnes of icebergs calve off and pass out of the fjord every year. Icebergs breaking from the glacier are often so large (up to 1 km in height) that they are too tall to float down the fjord and lie stuck on the bottom of its shallower areas, sometimes for years, until they are broken up by the force of the glacier and icebergs further up the fjord.

Studied for over 250 years, the Bloxshavn Glacier has helped develop modern understanding of climate change and icecap glaciology. Bloxshavn is one of the fastest-declining glaciers in the world, and icebergs calving from Bloxshavn were responsible for 4 percent of the increase in global sea level in the 20th century.